Amphotericin B Lipid Complex Therapy in an AIDS Patient with Rhodotorula rubra Fungemia
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چکیده
منابع مشابه
Nanodisks derived from amphotericin B lipid complex.
The goal of this study was to determine the effect of apolipoproteins on Amphotericin B lipid complex (ABLC). We report that incubation of ABLC with recombinant human apolipoprotein A-I (apoA-I) induces solubilization of ABLC by transforming the micron sized phospholipid/AMB assemblies into discrete nanoscale disk-shaped complexes termed nanodisks (ND). ApoA-I induced changes in ABLC solubility...
متن کاملControlled trials of amphotericin B lipid complex.
because it occurred in the midst of the usual seasonal increase in the number of cases of enteroviral meningitis together with cases of herpes simplex virus 1 (HSV-1) encephalitis, which occurs sporadically throughout the year. HSV-1 encephalitis may be differentiated from WNE by the presence of focal abnormalities on the electroencephalogram and/or on CT/MRI scans. Most cases of enteroviral me...
متن کاملSuccessful therapy of Candida pulcherrima fungemia in a premature newborn with liposomal amphotericin B and micafungin
New Candida species may cause bloodstream infections challenging current therapeutic approaches because of unpredictable susceptibility and virulence. In the present report, we describe a fungemia case due to Candida pulcherrima in a premature neonate. After full in vitro diagnostic workup, the neonate was successfully treated with liposomal amphotericin B and micafungin achieving rapid fungal ...
متن کاملRhodotorula minuta fungemia in a ewe lamb.
An 8-month-old crossbred ewe, normal upon physical examination, was humanely euthanized for tissue collection. After approximately 3 weeks in tissue culture, fungi began budding out of cells obtained from the choroid plexus. After an additional 3 weeks, budding was observed in kidney cell cultures and eventually in monocyte cultures as well. Serum from the lamb was submitted to the Veterinary D...
متن کاملDose-dependent pharmacokinetics of amphotericin B lipid complex in rabbits.
Amphotericin B lipid complex (ABLC) was recently approved by the Food and Drug Administration for treatment of patients with invasive fungal infections who are intolerant of or refractory to conventional amphotericin B therapy. Little is known, however, about the pharmacokinetics of this new antifungal compound. We therefore investigated the pharmacokinetics of ABLC in comparison with those of ...
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ژورنال
عنوان ژورنال: Clinical Infectious Diseases
سال: 1998
ISSN: 1058-4838,1537-6591
DOI: 10.1086/517159